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Proinflammatory effects of malondialdehyde in lymphocytes
Author(s) -
Raghavan Somasundaram,
Subramaniyam Ganesan,
Shanmugam Narkunaraja
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1211617
Subject(s) - proinflammatory cytokine , jurkat cells , malondialdehyde , biology , chemokine , signal transduction , cytokine , inflammation , immunology , reactive oxygen species , immune system , oxidative stress , microbiology and biotechnology , pharmacology , endocrinology , t cell
MDA changed cytokine/chemokines mRNA profiles in lymphocytes; increased cytokines expression is via oxidative stress, p38MAPK, and PKC pathways.