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Functional overlap but differential expression of CSF‐1 and IL‐34 in their CSF‐1 receptor‐mediated regulation of myeloid cells
Author(s) -
Wei Suwen,
Nandi Sayan,
Chitu Violeta,
Yeung YeeGuide,
Yu Wenfeng,
Huang Minmei,
Williams Lewis T.,
Lin Haishan,
Stanley E. Richard
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1209822
Subject(s) - biology , macrophage colony stimulating factor , macrophage , microbiology and biotechnology , receptor , in situ hybridization , osteoclast , signal transduction , messenger rna , in vitro , biochemistry , gene
CSF‐1 and the novel CSF‐1 receptor ligand, IL‐34, possess similar CSF‐1R‐mediated activities, but differ in their spatio‐temporal expression, permitting complementary CSF‐1 receptor activation in vivo.