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Pivotal Advance: Tumor‐mediated induction of myeloid‐derived suppressor cells and M2‐polarized macrophages by altering intracellular PGE 2 catabolism in myeloid cells
Author(s) -
Eruslanov Evgeniy,
Daurkin Irina,
Ortiz Javier,
Vieweg Johannes,
Kusmartsev Sergei
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1209821
Subject(s) - myeloid derived suppressor cell , arginase , myeloid , biology , cancer research , microbiology and biotechnology , immunology , suppressor , arginine , biochemistry , amino acid , gene
Tumors impair function of tumor‐infiltrated antigen‐presenting cells by altering intracellular PGE 2 catabolism in the myeloid cells.