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Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis
Author(s) -
McCaffrey Ramona L.,
Schwartz Justin T.,
Lindemann Stephen R.,
Moreland Jessica G.,
Buchan Blake W.,
Jones Bradley D.,
Allen LeeAnn H.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1209811
Subject(s) - nadph oxidase , biology , superoxide , respiratory burst , microbiology and biotechnology , francisella tularensis , oxidase test , secretion , phagosome , intracellular , biochemistry , reactive oxygen species , enzyme , gene , virulence
Francisella tularensis uses both pre‐ and post‐assembly mechanisms to inhibit NADPH oxidase activity at its own phagosome and throughout infected human neutrophils.

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