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T cell immunoglobulin‐ and mucin‐domain‐containing molecule‐4 attenuates concanavalin A‐induced hepatitis by regulating macrophage
Author(s) -
Xu Liyun,
Qi Jianni,
Zhao Peiqing,
Liang Xiaohong,
Ju Ying,
Liu Peng,
Liu Bing,
Guo Chun,
Zhang Lining,
Ma Chunhong,
Gao Lifen
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1209797
Subject(s) - cd80 , cd86 , biology , adoptive cell transfer , immunology , macrophage , secretion , t cell , cd40 , in vitro , endocrinology , immune system , biochemistry , cytotoxic t cell
Tim‐4 plays an important role in preventing liver injury through inhibition of CD80, CD86, and MHC II expression and TNF‐α secretion by macrophages.