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Endogenous ligands of TLR2 and TLR4: agonists or assistants?
Author(s) -
Erridge Clett
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1209775
Subject(s) - tlr2 , tlr4 , biology , endogeny , intracellular , microbiology and biotechnology , receptor , toll like receptor , signal transduction , innate immune system , biochemistry
Review summarizes the evidence supporting the existence of endogenous ligands of TLR2 and TLR4 and proposes that many may be better described as PAMP‐sensitizing molecules.