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Pivotal Advance: Glycyrrhizin restores the impaired production of β‐defensins in tissues surrounding the burn area and improves the resistance of burn mice to Pseudomonas aeruginosa wound infection
Author(s) -
Yoshida Tsuyoshi,
Yoshida Shohei,
Kobayashi Makiko,
Herndon David N.,
Suzuki Fujio
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1208760
Subject(s) - glycyrrhizin , antimicrobial , pseudomonas aeruginosa , microbiology and biotechnology , sepsis , biology , burn injury , antimicrobial peptides , burn wound , pharmacology , immunology , wound healing , bacteria , medicine , surgery , genetics
Glycyrrhizin improves the resistance of burn mice to Pseudomonas aeruginosa burn wound infection through inhibiting IL‐10 and/or CCL2 production by Gr‐1 + CD11b + cells.