Premium
PPARγ regulates retinoic acid‐mediated DC induction of Tregs
Author(s) -
Housley William J.,
O'Conor Catherine A.,
Nichols Frank,
Puddington Lynn,
Lingenheld Elizabeth G.,
Zhu Li,
Clark Robert B.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1208733
Subject(s) - foxp3 , retinoic acid , autoimmunity , biology , regulator , secretion , immune system , microbiology and biotechnology , immunology , il 2 receptor , receptor , peroxisome proliferator activated receptor , endogeny , in vivo , cancer research , endocrinology , t cell , cell culture , biochemistry , genetics , gene
PPARγ plays a significant role in the induction of regulatory T cells (Tregs) by DC and can mediate enhanced conversion via secretion of retinoic acid.