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The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML‐RARα in APL
Author(s) -
Humbert Magali,
Federzoni Elena A.,
Britschgi Adrian,
Schläfli Anna M.,
Valk Peter J. M.,
Kaufmann Thomas,
Haferlach Torsten,
Behre Gerhard,
Simon HansUwe,
Torbett Bruce E.,
Fey Martin F.,
Tschan Mario P.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1112608
Subject(s) - gene knockdown , biology , ectopic expression , cancer research , transcription factor , myeloid , transcription (linguistics) , haematopoiesis , effector , microbiology and biotechnology , gene , stem cell , genetics , linguistics , philosophy
Transcriptional mechanisms responsible for low DAPK2 levels in particular AML subtypes.