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Liver X receptor activation inhibits osteoclastogenesis by suppressing NF‐κB activity and c‐Fos induction and prevents inflammatory bone loss in mice
Author(s) -
Kim HyunJu,
Yoon KyungAe,
Yoon HyeJin,
Hong Jung Min,
Lee MinJung,
Lee InKyu,
Kim ShinYoon
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1112601
Subject(s) - liver x receptor , rankl , osteoclast , bone resorption , agonist , endocrinology , medicine , nf κb , biology , nuclear receptor , microbiology and biotechnology , cancer research , signal transduction , transcription factor , receptor , chemistry , activator (genetics) , biochemistry , gene
Liver X receptors may have potential as therapeutic targets for bone resorption‐associated diseases.
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