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Characteristics of TCR/CD3 complex CD3ɛ chains of regulatory CD4 + T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo
Author(s) -
Rojo Jose M.,
Ojeda Gloria,
Acosta Yenny Y.,
MontesCasado Maria,
Criado Gabriel,
Portolés Pilar
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1112584
Subject(s) - t cell receptor , cd3 , foxp3 , biology , immunology , antigen , microbiology and biotechnology , il 2 receptor , immune system , t cell , cd8
CD4 Treg cells have quantitative and qualitative differences in the TCR/CD3 complex, particularly concerning CD3ɛ chains; differences may reconcile conflicting models of Treg differentiation.
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