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Autoinflammation: translating mechanism to therapy
Author(s) -
Doherty Taylor A.,
Brydges Susannah D.,
Hoffman Hal M.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1110616
Subject(s) - biology , innate immune system , inflammasome , nalp3 , mechanism (biology) , inflammation , immunology , computational biology , bioinformatics , immune system , neuroscience , philosophy , epistemology
Review discusses autoinflammatory diseases as a new classification of immune disorders due to dysregulated innate immunity yet sensitive to targeted cytokine therapy.