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Interferon‐γ‐secreting NK cells promote induction of dry eye disease
Author(s) -
Chen Yihe,
Chauhan Sunil K.,
Saban Daniel R.,
Sadrai Zahra,
Okanobo Andre,
Dana Reza
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1110611
Subject(s) - biology , immunology , innate lymphoid cell , immune system , proinflammatory cytokine , inflammation , priming (agriculture) , interleukin 12 , interleukin 21 , in vivo , effector , acquired immune system , janus kinase 3 , microbiology and biotechnology , in vitro , t cell , cytotoxic t cell , biochemistry , botany , germination
NK cells participate in the induction of dry eye disease via secretion of IFNγ which acts on both target tissue and secondary lymphoid tissue.