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IL‐15 ex vivo overcomes CD4 + T cell deficiency for the induction of human antigen‐specific CD8 + T cell responses
Author(s) -
Yu Huifeng,
TawabAmiri Abdul,
Dzutsev Amiran,
Sabatino Marianna,
Aleman Karen,
Yarchoan Robert,
Terabe Masaki,
Sui Yongjun,
Berzofsky Jay A.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1010579
Subject(s) - biology , cd8 , immunology , t cell , ex vivo , cytotoxic t cell , immune system , antigen , peripheral blood mononuclear cell , in vivo , cancer research , in vitro , biochemistry , microbiology and biotechnology
IL‐15 overcomes CD4 + T cell deficiency in vitro in induction of recall CD8 + T cell responses after CD4 depletion or HIV infection.