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Biphasic activity of CD137 ligand‐stimulated monocytes on T cell apoptosis and proliferation
Author(s) -
Kwajah M. M. Shaqireen,
Mustafa Nurulhuda,
Holme Andrea L.,
Pervaiz Shazib,
Schwarz Herbert
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1010569
Subject(s) - biology , microbiology and biotechnology , t cell , apoptosis , cytotoxic t cell , programmed cell death , antigen presenting cell , monocyte , cell growth , natural killer t cell , immunology , immune system , biochemistry , in vitro
CD137 ligand signaling causes peripheral human monocytes to induce apoptosis in T cells initially, and differentiation to dendritic cells that activate T cells, subsequently.