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Identification of hamster inducible nitric oxide synthase ( iNOS ) promoter sequences that influence basal and inducible iNOS expression
Author(s) -
Saldarriaga Omar A.,
Travi Bruno L.,
Choudhury Goutam Ghosh,
Melby Peter C.
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1010568
Subject(s) - hamster , biology , microbiology and biotechnology , promoter , mesocricetus , transcription factor , transcription (linguistics) , nitric oxide synthase , response element , nitric oxide , gene expression , gene , biochemistry , endocrinology , linguistics , philosophy
The low expression of iNOS in hamsters is related to a region of the proximal promoter that lacks an NF‐IL6 binding element.