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Rat resident testicular macrophages have an alternatively activated phenotype and constitutively produce interleukin‐10 in vitro
Author(s) -
Winnall Wendy R.,
Muir Julie A.,
Hedger Mark P.
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1010557
Subject(s) - biology , immune privilege , proinflammatory cytokine , microbiology and biotechnology , immune system , cd163 , interleukin 10 , t cell , immunology , phenotype , inflammation , gene , biochemistry
Resident rat testicular macrophages exhibit a gene expression pattern consistent with immunosuppression, both before and after stimulation with lipopolysaccharide and/or cytokines.