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Characterization of the interaction between serum mannan‐binding protein and nucleic acid ligands
Author(s) -
Nakamura Natsuko,
aka Motohiro,
Ma Bruce Yong,
Matsumoto Shogo,
Kawasaki Nobuko,
Asano Shinji,
Kawasaki Toshisuke
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1008674
Subject(s) - mannan binding lectin , biology , collectin , c type lectin , nucleic acid , dna , lectin , lectin pathway , microbiology and biotechnology , phagocytosis , complement system , innate immune system , immune system , biochemistry , classical complement pathway , immunology
Serum C‐type lectin MBP is shown to bind DNA and RNA from bacteria, plasmids, synthetic oligonucleotides, and fragmented DNA of apoptotic cells via its carbohydrate recognition domain.