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CC chemokine ligand‐2 synergizes with the nonchemokine G protein‐coupled receptor ligand fMLP in monocyte chemotaxis, and it cooperates with the TLR ligand LPS via induction of CXCL8
Author(s) -
Gouwy Mieke,
Struyf Sofie,
Verbeke Hannelien,
Put Willy,
Proost Paul,
Opdenakker Ghislain,
Van Damme Jo
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1008638
Subject(s) - chemotaxis , chemokine , biology , ccr2 , monocyte , ccl2 , interleukin 8 , chemokine receptor , microbiology and biotechnology , cxc chemokine receptors , immunology , receptor , innate immune system , immune system , cytokine , biochemistry
Novel mechanism of enhancing monocyte chemotaxis during bacterial infections with gram‐negative bacteria demonstrates the importance of local contexts in inflammatory and infectious insults.