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A new function of the Fas‐FasL pathway in macrophage activation
Author(s) -
Chakour Reza,
Allenbach Cindy,
Desgranges Florian,
Charmoy Mélanie,
Mauel Jacques,
Garcia Irène,
Launois Pascal,
Louis Jacques,
TacchiniCottier Fabienne
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1008590
Subject(s) - fas ligand , biology , macrophage , microbiology and biotechnology , signal transduction , secretion , intracellular , tumor necrosis factor alpha , interferon gamma , apoptosis , immunology , cytokine , programmed cell death , in vitro , biochemistry
Triggering of the Fas/Fas ligand pathway leads to macrophage activation and to the induction of microbicidal activity in macrophages infected with Leishmania major .