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Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter
Author(s) -
Shoenfelt Joanna,
Mitkus Robert J.,
Zeisler Rolf,
Spatz Rabia O.,
Powell Jan,
Fenton Matthew J.,
Squibb Katherine A.,
Medvedev Andrei E.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1008587
Subject(s) - tlr4 , tlr2 , proinflammatory cytokine , cytokine , biology , chemokine , tumor necrosis factor alpha , immunology , inflammation , microbiology and biotechnology
Fine and coarse air pollution particles signal macrophage activation via differential utilization of Toll‐like receptors (TLR) 2 and TLR4 but shared use of the MyD88 signaling pathway.