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HMGB1 loves company
Author(s) -
Bianchi Marco E.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.1008585
Subject(s) - hmgb1 , biology , inflammation , microbiology and biotechnology , tlr2 , proinflammatory cytokine , innate immune system , tlr4 , receptor , immunology , stimulus (psychology) , chemotaxis , immune system , genetics , psychology , psychotherapist
HMGB1 outside of a cell is both a trigger of inflammation and a stimulus for tissue reconstruction; the balance may depend on the complexes it forms with other molecules.