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Cot/tpl2 participates in the activation of macrophages by adiponectin
Author(s) -
SanzGarcia Carlos,
Nagy Laura E.,
Lasunción Miguel A.,
Fernandez Margarita,
Alemany Susana
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0913486
Subject(s) - biology , adiponectin , microbiology and biotechnology , macrophage , endocrinology , biochemistry , in vitro , insulin resistance , insulin
Adiponectin is a new signal that activates Erk1/2 through the IKKβ‐p105/NFκB1‐Cot/tpl2 intracellular pathway in macrophages; this cassette mediates the activation of macrophages by this hormone.
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