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mTOR limits the recruitment of CD11b + Gr1 + Ly6C high myeloid‐derived suppressor cells in protecting against murine immunological hepatic injury
Author(s) -
Zhang Yan,
Bi Yujing,
Yang Hui,
Chen Xi,
Liu Huanrong,
Lu Yun,
Zhang Zhengguo,
Liao Jiongbo,
Yang Shan,
Chu Yiwei,
Yang Ruifu,
Liu Guangwei
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0913473
Subject(s) - pi3k/akt/mtor pathway , integrin alpha m , immune system , biology , cancer research , innate immune system , context (archaeology) , immunology , microbiology and biotechnology , signal transduction , paleontology
mTOR signaling is a pivotal negative determinant of MDSC recruitments in immune‐mediated hepatic injury diseases.