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Bacterial reprogramming of PBMCs impairs monocyte phagocytosis and modulates adaptive T cell responses
Author(s) -
André Maya C.,
Gille Christian,
Glemser Philip,
Woiterski Jeanette,
Hsu HsinYun,
Spring Baerbel,
Keppeler Hildegard,
Kramer Boris W.,
Handgretinger Rupert,
Poets Christian F.,
Lauber Kirsten,
Orlikowsky Thorsten W.
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0911474
Subject(s) - biology , phagocytosis , proinflammatory cytokine , immunology , immune system , monocyte , acquired immune system , reprogramming , context (archaeology) , cd14 , mononuclear phagocyte system , inflammation , microbiology and biotechnology , cell , paleontology , genetics
Bacterial re‐programming of PBMC‐derived monocytes induces the emergence of a distinct monocytic phenotype with profound phagocytic impairments but a preserved ability for naïve T cell stimulation.