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Phagosomal retention of Francisella tularensis results in TIRAP/Mal‐independent TLR2 signaling
Author(s) -
Cole Leah E.,
Laird Michelle H. W.,
Seekatz Anna,
Santiago Araceli,
Jiang Zhaozhao,
Barry Eileen,
Shirey Kari Ann,
Fitzgerald Katherine A.,
Vogel Stefanie N.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0909619
Subject(s) - francisella tularensis , biology , francisella , microbiology and biotechnology , tularemia , tlr2 , virology , immunology , innate immune system , immune system , genetics , virulence , gene
Enhanced or prolonged interaction between an agonist and TLR2 can overcome the need for TIRAP.