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The battlefield of perforin/granzyme cell death pathways
Author(s) -
Hoves Sabine,
Trapani Joseph A.,
Voskoboinik Ilia
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0909608
Subject(s) - biology , perforin , granzyme , microbiology and biotechnology , programmed cell death , proteases , granzyme b , cytotoxic t cell , effector , immunological synapse , immune system , granzyme a , apoptosis , t cell , immunology , cd8 , genetics , t cell receptor , biochemistry , enzyme , in vitro
The review discusses the controversies in the field of cytotoxic lymphocyte secretory granule death pathways.