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Distinct populations of metastases‐enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra‐abdominal tumor
Author(s) -
Connolly Michael K.,
MallenSt. Clair Jon,
Bedrosian Andrea S.,
Malhotra Ashim,
Vera Valery,
Ibrahim Junaid,
Henning Justin,
Pachter H. Leon,
BarSagi Dafna,
Frey Alan B.,
Miller George
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0909607
Subject(s) - biology , immune system , cytotoxic t cell , cancer research , chemokine , integrin alpha m , phenotype , myeloid , immunology , liver cancer , metastasis , tumor microenvironment , cancer , in vitro , hepatocellular carcinoma , gene , biochemistry , genetics
The expansion of distinct immune suppressive cells in the liver of tumor bearing hosts may bear on the propensity of patients with intra‐abdominal cancers to develop liver metastases.