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Ethyl pyruvate administration inhibits hepatic tumor growth
Author(s) -
Liang Xiaoyan,
Romo de Vivar Chavez Antonio,
Schapiro Nicole E.,
Loughran Patricia,
Thorne Stephen H.,
Amoscato Andrew A.,
Zeh Herbert J.,
Beer–Stolz Donna,
Lotze Michael T.,
Vera Michael E.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0908578
Subject(s) - apoptosis , biology , inflammation , endocrinology , medicine , immune system , cancer research , cell growth , liver tumor , immunology , hepatocellular carcinoma , biochemistry , genetics
The first demonstration of ethyl pyruvate inhibition of liver tumor growth associated with induction of tumor apoptosis, diminished HMGB1 release, and decreased inflammation is reported.