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Delaying the onset of experimental autoimmune encephalomyelitis with the microtubule‐stabilizing compounds, paclitaxel and Peloruside A
Author(s) -
Crume Kevin P.,
O'Sullivan David,
Miller John H.,
Northcote Peter T.,
La Flamme Anne C.
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0908541
Subject(s) - experimental autoimmune encephalomyelitis , paclitaxel , biology , microtubule , immunology , encephalomyelitis , neuroscience , microbiology and biotechnology , multiple sclerosis , chemotherapy , genetics
Microtubule‐stabilizing drugs able to delay the onset of CNS disease in an MS mouse model depends on altering both the lymphoid and myeloid cell compartments.