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Galectin‐8 provides costimulatory and proliferative signals to T lymphocytes
Author(s) -
Tribulatti María Virginia,
Cattaneo Valentina,
Hellman Ulf,
Mucci Juan,
Campetella Oscar
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0908529
Subject(s) - biology , t cell , galectin , microbiology and biotechnology , t cell receptor , immune system , antigen , t lymphocyte , major histocompatibility complex , immunology
CD4+ T cells are the main lymphocyte target of Galectin‐8, which lowers their activation threshold and thus suggesting the lectin involvement in inflammatory diseases.