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Virus‐specific CD4 and CD8 T cell responses in the absence of Th1‐associated transcription factors
Author(s) -
Mollo Sarah B.,
Ingram Jennifer T.,
Kress Robert L.,
Zajac Allan J.,
Harrington Laurie E.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0813429
Subject(s) - biology , effector , stat4 , cytotoxic t cell , transcription factor , cd8 , microbiology and biotechnology , phenotype , t cell , transcription (linguistics) , immunology , antigen , immune system , signal transduction , genetics , in vitro , gene , stat , linguistics , philosophy , stat3
Tbet and STAT4 have distinct roles in effector T cell differentiation, but are not required for generation of T cell memory.
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