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Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes
Author(s) -
Paley Michael A.,
Gordon Scott M.,
Bikoff Elizabeth K.,
Robertson Elizabeth J.,
Wherry E. John,
Reiner Steven L.
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0812400
Subject(s) - biology , cytotoxic t cell , microbiology and biotechnology , transcription factor , effector , cd8 , green fluorescent protein , reporter gene , immune system , immunology , gene expression , genetics , gene , in vitro
Fluorescent reporter allele provides insights on the role for eomesodermin in NK development, CD8 + T cell effector function, and central memory formation.