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CCR7 ligands up‐regulate IL‐23 through PI3‐kinase and NF‐κB pathway in dendritic cells
Author(s) -
Kuwabara Taku,
Tanaka Yuriko,
Ishikawa Fumio,
Kondo Motonari,
Sekiya Hideki,
Kakiuchi Terutaka
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0811415
Subject(s) - ccl19 , c c chemokine receptor type 7 , microbiology and biotechnology , ccl21 , chemokine , biology , pi3k/akt/mtor pathway , nf κb , p38 mitogen activated protein kinases , ly294002 , signal transduction , mapk/erk pathway , cancer research , immunology , chemokine receptor , immune system
CCR7 ligands activate PI3‐kinase and NF‐κB pathways in DC to induce the expression of IL‐23p19.