Premium
IFN‐α produced by human plasmacytoid dendritic cells enhances T cell‐dependent naïve B cell differentiation
Author(s) -
Gujer Cornelia,
Sandgren Kerrie J.,
Douagi Iyadh,
Adams William C.,
Sundling Christopher,
SmedSörensen Anna,
Seder Robert A.,
Hedestam Gunilla B. Karlsson,
Loré Karin
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0810460
Subject(s) - cd40 , cd86 , cd80 , biology , naive b cell , b cell , antigen presenting cell , il 2 receptor , microbiology and biotechnology , b 1 cell , cd19 , interleukin 21 , cytotoxic t cell , mhc class ii , t cell , immune system , immunology , antibody , in vitro , biochemistry
Plasmacytoid dendritic cells via their production of IFN‐α render B cells more receptive to T cell contact which facilitates B cell proliferation and differentiation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom