Premium
Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1
Author(s) -
Arimilli Subhashini,
Sharma Sharad K.,
Yammani Rama,
Reid Sean D.,
Parks Griffith D.,
AlexanderMiller Martha A.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0809575
Subject(s) - effector , biology , orai1 , microbiology and biotechnology , stim1 , lung , extracellular , function (biology) , calcium , cd8 , immunology , immune system , medicine , endoplasmic reticulum
A previously unknown mechanism for the active negative regulation of function in effector T cells is described.