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A conserved distal segment of the mouse CSF‐1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice
Author(s) -
Ovchinnikov Dmitry A.,
DeBats Claire E. E.,
Sester David P.,
Sweet Matthew J.,
Hume David A.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0809557
Subject(s) - biology , microbiology and biotechnology , trophoblast , promoter , reporter gene , gene , exon , gene expression , regulatory sequence , transgene , tata box , genetically modified mouse , messenger rna , placenta , genetics , pregnancy , fetus
Osteoclasts initiate transcription of the CSF‐1 receptor gene from a distinct location upstream of the major macrophage transcription start sites.