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CD70 expression by dendritic cells plays a critical role in the immunogenicity of CD40‐independent, CD4 + T cell‐dependent, licensed CD8 + T cell responses
Author(s) -
Van Deusen Katherine E.,
Rajapakse Rohan,
Bullock Timothy N. J.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0809535
Subject(s) - cd40 , biology , cd8 , t cell , cytotoxic t cell , immunogenicity , microbiology and biotechnology , priming (agriculture) , cd28 , immunology , immune system , in vitro , biochemistry , botany , germination
Helper‐dependent, CD40‐independent, CD8 + T cell responses are shown to be CD70‐dependent, demonstrating alternative mechanisms by which CD4 + T cells induce CD70 expression on DC.