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Technical Advance: A new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells
Author(s) -
Rissiek Björn,
Danquah Welbeck,
Haag Friedrich,
KochNolte Friedrich
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0713407
Subject(s) - natural killer t cell , biology , adoptive cell transfer , cytolysis , microbiology and biotechnology , ex vivo , cell sorting , cell , cd1d , function (biology) , in vitro , t cell , immunology , biochemistry , immune system , cytotoxic t cell
New method to prepare functional Tregs and NKT cells by injecting an ARTC2‐blocking nanobody that prevents activation of the cytolytic P2X7 receptor during cell preparation.