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HIV‐1 envelope–receptor interactions required for macrophage infection and implications for current HIV‐1 cure strategies
Author(s) -
Gorry Paul R.,
Francella Nicholas,
Lewin Sharon R.,
Collman Ronald G.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0713368
Subject(s) - biology , human immunodeficiency virus (hiv) , tropism , cxcr4 , macrophage , mechanism (biology) , immunology , pathogenesis , receptor , tissue tropism , virology , virus , microbiology and biotechnology , chemokine , inflammation , genetics , in vitro , philosophy , epistemology
Review of the alternative ways HIV‐1 Env proteins can adapt to permit macrophage infection, and the role of macrophages as persistent viral reservoirs.

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