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Implication of indolamine 2,3 dioxygenase in the tolerance toward fetuses, tumors, and allografts
Author(s) -
Dürr Sophie,
Kindler Vincent
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0712347
Subject(s) - biology , immune system , fetus , immune tolerance , immunology , trophoblast , pregnancy , cancer research , placenta , genetics
Review on indolamine 2,3 dioxygenase as required to maintain peripheral tolerance, but if activated too vigorously, may impair pathogen tumor clearance or eradication.
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