z-logo
Premium
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development
Author(s) -
Savino Maria Teresa,
Ulivieri Cristina,
Emmi Giacomo,
Prisco Domenico,
De Falco Giulia,
Ortensi Barbara,
Beccastrini Enrico,
Emmi Lorenzo,
Pelicci Giuliana,
DˈElios Mario M.,
Baldari Cosima T.
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0712331
Subject(s) - biology , autoimmunity , proinflammatory cytokine , immunology , lupus nephritis , t cell , microbiology and biotechnology , regulator , effector , signal transducing adaptor protein , signal transduction , cancer research , inflammation , immune system , medicine , disease , biochemistry , gene
Rai prevents lupus nephritis by impairing the development and expansion of both proinflammatory Th17 and Th1 cells.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here