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Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G
Author(s) -
Gibson Andrew W.,
Li Xinrui,
Wu Jianming,
Baskin Julie G.,
Raman Chander,
Edberg Jeffrey C.,
Kimberly Robert P.
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0711368
Subject(s) - phosphoserine , lipid raft , biology , phosphorylation , microbiology and biotechnology , serine , transport protein , immunoprecipitation , receptor , signal transduction , biochemistry , gene
Serine phosphorylation of the FcγRI CY domain directs its migration to lipid rafts and its interaction with protein 4.1G, suggesting a tethering role for protein 4.1G.