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High MafB expression following burn augments monocyte commitment and inhibits DC differentiation in hemopoietic progenitors
Author(s) -
Howell Kirstin,
Posluszny Joseph,
He Li K.,
Szilagyi Andrea,
Halerz John,
Gamelli Richard L.,
Shankar Ravi,
Muthu Kuzhali
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0711338
Subject(s) - monocyte , bone marrow , haematopoiesis , immunology , progenitor cell , cd11c , biology , burn injury , sepsis , population , microbiology and biotechnology , cancer research , medicine , stem cell , phenotype , biochemistry , surgery , environmental health , gene
Burn injury augments monocyte commitment and abrogates DC differentiation through increased MCSF‐receptors and decreased GATA‐1 expressions orchestrated by high MafB in hematopoietic granulocyte‐monocyte progenitor cells.