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Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration
Author(s) -
Brigotti Maurizio,
Tazzari Pier Luigi,
Ravanelli Elisa,
Carnicelli Domenica,
Barbieri Stefania,
Rocchi Laura,
Arfilli Valentina,
Scavia Gaia,
Ricci Francesca,
Bontadini Andrea,
Alfieri Roberta R.,
Petronini Pier Giorgio,
Pecoraro Carmine,
Tozzi Alberto E.,
Caprioli Alfredo
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0709475
Subject(s) - proinflammatory cytokine , shiga toxin , biology , toxin , in vitro , cytokine , endothelial stem cell , immunology , interleukin 8 , tumor necrosis factor alpha , microbiology and biotechnology , inflammation , biochemistry , escherichia coli , gene
Intoxicated endothelial cells release pro‐inflammatory cytokines involved in renal damage; amount of cytokines inversely correlates with the amount of toxin carried by PMN.