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Stanniocalcin‐1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2
Author(s) -
Wang Yanlin,
Huang Luping,
Abdelrahim Maen,
Cai Qingsong,
Truong Anh,
Bick Roger,
Poindexter Brian,
SheikhHamad David
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0708454
Subject(s) - superoxide , biology , mitochondrion , microbiology and biotechnology , macrophage , chemokine , reactive oxygen species , apoptosis , immune system , immunology , biochemistry , in vitro , enzyme
Mammalian stanniocalcin‐1, a secreted phosphogylcoprotein that targets the mitochondria, suppresses superoxide and may function as an LPS antagonist in macrophages.