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Human defensins activate monocyte‐derived dendritic cells, promote the production of proinflammatory cytokines, and up‐regulate the surface expression of CD91
Author(s) -
Presicce Pietro,
Giannelli Stefania,
Taddeo Adriano,
Villa Maria Luisa,
Della Bella Silvia
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0708412
Subject(s) - proinflammatory cytokine , biology , cd80 , microbiology and biotechnology , cd86 , innate immune system , beta defensin , acquired immune system , immune system , immunology , cytokine , cd40 , inflammation , t cell , in vitro , cytotoxic t cell , biochemistry
Immunostimulatory properties of defensins on DC promote maturation and proinflammatory response.