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Macrophage uptake and accumulation of folates are polarization‐dependent in vitro and in vivo and are regulated by activin A
Author(s) -
Samaniego Rafael,
Palacios Blanca Soler,
DomiguezSoto Ángeles,
Vidal Carlos,
Salas Azucena,
Matsuyama Takami,
SánchezTorres Carmen,
Torre Inmaculada,
MirandaCarús Maria Eugenia,
SánchezMateos Paloma,
PuigKröger Amaya
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0613345
Subject(s) - biology , macrophage , in vivo , macrophage polarization , in vitro , microbiology and biotechnology , macrophage colony stimulating factor , transporter , downregulation and upregulation , biochemistry , gene , genetics
Folate handling is dependent on the macrophage polarization state, where folate metabolism could provide useful diagnostic or therapeutic markers for inflammatory pathologies.