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Technical Advance: Langerhans cells derived from a human cell line in a full‐thickness skin equivalent undergo allergen‐induced maturation and migration
Author(s) -
Ouwehand Krista,
Spiekstra Sander W.,
Waaijman Taco,
Scheper Rik J.,
Gruijl Tanja D.,
Gibbs Susan
Publication year - 2011
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0610374
Subject(s) - langerin , epidermis (zoology) , compartment (ship) , biology , human skin , microbiology and biotechnology , langerhans cell , fibroblast , birbeck granules , immunology , cell culture , dendritic cell , in vitro , immune system , biochemistry , anatomy , oceanography , genetics , geology
New method to develop a human skin‐equivalent containing LC‐like cells in vitro, under conditions that mimic the natural tissue composition.