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Heterogeneity in a mouse model of histiocytosis: transformation of Langerin + dendritic cells, macrophages, and precursors
Author(s) -
Leenen Pieter J. M.,
Bechan Gitanjali I.,
Melis Marleen,
Broeder Berlinda J. H.,
Löhler Jürgen,
Egeler R. Maarten
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0609432
Subject(s) - biology , langerin , homing (biology) , phenotype , histiocyte , population , cd8 , immunology , spleen , dendritic cell , pathology , cancer research , immune system , genetics , medicine , ecology , environmental health , gene
Mouse histiocytosis sarcoma virus infection induces a heterogeneous disease with characteristics of Mφ/DC neoplasms involving Langerin+ DC, Mφ, and precursors.